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January 28, 2010

Elderberry highest in antioxidants?

I blogged about a study that showed that Elderberry could be as useful as Tamiflu in fighting H1N1 virus and other flu viruses. I just stumbled upon a table showing that the elderberry has almost the highest ORAC (Oxygen Radical Absorbance Capacity) value of any berry.

ORAC scores are for 100/grams (3.5 ounces).

  • Aronia (15.8K ORAC)
  • Elderberry (14.6K ORAC)
  • Cranberries (9.5K ORAC)
  • Black Currant (8K ORAC)
  • Blueberries (6K ORAC)
  • Blackberries (6K ORAC)
  • Plums (6K ORAC)
  • Glass of Cabernet Sauvignon (5K ORAC)
  • Glass of red table wine or Chianti (3.8K ORAC)
  • Red grape Juice (1.2K ORAC)
Also topping any overall list of antioxidant foods is cocoa.  Raw cocoa has an ORAC of 26,000 per 100/g; processed dark chocolate about half that (processing heat will reduce a food's antioxidant properties).

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    January 27, 2010

    Barefoot running and the fore-foot strike

    J. Fallows, runner and journalist, blogs that according to a report in Nature, "fore-foot running, which also turns out to be the way people naturally run if they're barefoot, is fundamentally much easier on your joints and bones and therefore easier to bear over the years."

    Good to know scientists are finally studying the question. I'm not a regular bare-foot runner yet -- though I have been won over to wearing lightweight running shoes.  

    More on the question of the best footwear for running in a future post.

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    January 26, 2010

    Chondrolysis caused by pain pumps

    Some medical stories make me furious. This is one of them. NY Times:

    Chondrolysis has ended the athletic careers of dozens of high school and college students. In the most severe cases, it has required joint replacements. Many sufferers face lifetimes of pain and disability.

    “I’ve lost so many hours of sleep over this, I can’t tell you,” said Dr. David S. Bailie, an orthopedic surgeon in Scottsdale, Ariz., who said he had seen dozens of cases of chondrolysis since 2005. “There’s nothing worse than a surgeon doing something that causes a problem, not fixes a problem.”

    Although it is still unknown why chondrolysis develops, several medical studies have concluded that a likely culprit is a pain pump, a postsurgical medical device used to deliver local anesthetics to a specific area through a plastic tube.

    What's really going on here?  Why are people being implanted with high-tech devices for the localized control of pain?   I've had more shoulder operations than anyone I know, and I'll tell you, shoulder pain goes away if you take demerol or morphine.  I've been prescribed these medicines on numerous occasions and they work. 

    Kids are having these weird, untested, and dangerous devices put into their bodies because the medical establishment is adverse to prescribing ordinary pain killers to people in pain.   These medicines work and they are far safer than any high-tech alternatives.   Part of the interest in these devices might be lowering hospital costs because administering morphine requires an extended hospital stay.  Ultimately, a confluence of corporate interests -- manufacturers and the insurance companies -- are likely behind the interest in pushing these devices.  That's why mainly only American kids are being implanted with these high-tech devices.  

    The article continues:
    In late 2006, after a handful of studies indicated that the pain pumps might be causing chondrolysis, the I-Flow Corporation, the largest pump manufacturer, changed its directions in package inserts to advise doctors to avoid placing the pump catheters in joints. In 2007, I-Flow posted a bulletin on its Web site notifying physicians of the risk.

    The first lawsuits against pain pump companies were filed about two years ago. It is difficult to know the exact number of suits, but I-Flow reported in November that it was a defendant in 191 chondrolysis cases involving 412 patients. Of those, the company said, 80 suits were dismissed. Kay Jackson, a spokeswoman for the Kimberly-Clark Corporation, which purchased I-Flow last year, declined to comment, citing the pending litigation.
    I'm not a doctor, but over the years I've picked up a few basics of orthopedics.  First things: You don't go putting tubes into joints!   Certainly not to control pain. Any physician who would suggest doing this is an complete idiot.  (The risk of infection from the insertion of such a device is too great.  Pain-killing does not warrant such a risk.)  

    These companies deserve to be sued.  The first maxim of medicine is DO NO HARM.  That means don't go experimenting with unproven techniques in order to relieve pain -- pain that has safely been controlled for many decades through the non-localized administration of low-cost prescription medication.

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    January 25, 2010

    Exercise quote

    Dr. Robert Sallis, co-director of sports medicine at Fontana Medical Center in California:

    "Exercise can be used like a vaccine to prevent disease and a medication to treat disease. If there were a drug with the same benefits as exercise, it would instantly be the standard of care."

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    Oracea just expensive doxycycline?

    I just saw a commercial for a product called Oracea.  Oracia is "a low-dose form of doxycycline" for the treatment of a skin condition known as rosacea.

    Doxycycline ought to cost no more than $10 a month, but Oracea costs $200.    I did some checking on the Internet, and Oracea may be the poster-child for health-care costs run amok (h/t rosacea support):

    KUNC: The Big Zit Rip-off, Marc Ringel
    GREELEY, CO (2009-05-18) Most agree that something needs to be done to overhaul America’s healthcare system. But leave it to KUNC commentator Dr. Marc Ringel to illustrate the problem – through something as small and innocuous as a pimple.
    Or you can buy Oracea, a brand-name doxycycline marketed by Galderma Laboratories. Oracea will set you back over $200 a month if you purchase it in this country or about $150 if you shop online and make your buy from a Canadian outfit. To be sure, the dosage of Oracea is 40mg, making it, like the baby bear’s porridge, just right.

    I cannot imagine, though, how the extra 10 mg in a 50 mg generic doxycycline capsule could cause close to the distress that too-hot or too-cold porridge did to Goldilocks. Nor do I see how Oracea would work better than the plain vanilla generic except, perhaps, for an enhanced placebo effect generated by spending so much money on a product marketed especially to this affliction. A person might figure that such an exorbitantly expensive brand name would just have to work better.
    Oracea is claimed to have this advantage over doxycycline:
    Oracea is able to maintain a sustained release of the active ingredient doxycycline without venturing into anti-microbial territory. The advantage of a delayed release product is that Oracea can offer the `area under the concentration-by-time curve’ delivery, but at sub-antimicrobial dosage over 24 hours.

    That is, Oracea can deliver a dosage of doxycycline that can give measurable results, but keep the concentration of doxycycline in your blood low enough to reduce potential problems associated with antibiotics.
    If you are interested in researching this question further, the Rosacea support group website looks like a good place to start.

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